| CPC A61M 60/122 (2021.01) [A61M 60/808 (2021.01); A61M 60/237 (2021.01)] | 18 Claims |

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1. A method of supporting circulation in a descending aorta of a subject, comprising:
advancing an expandable pump portion of a blood pump into a descending aorta of a subject, the pump portion comprising an expandable blood conduit comprising a scaffold coupled to a membrane between a pump inflow and a pump outflow, the pump portion further including first and second expandable impellers at least partially within the blood conduit;
expanding the expandable blood conduit to an expanded and deployed configuration within the descending aorta;
expanding the first expandable impeller into an expanded configuration at least partially within the blood conduit;
expanding the second expandable impeller into an expanded configuration at least partially within the blood conduit and having a portion that extends beyond the expandable blood conduit; and
rotating the first and second expandable impellers to thereby move blood into the pump portion, through the blood conduit, and out of the pump portion, wherein rotation of the portion of the second expandable impeller that extends beyond the expandable blood conduit causes the pump outflow to include a radial flow component.
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