US 12,409,253 B2
Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers
David E. Babcock, Brooklyn Park, MN (US); Timothy M. Kloke, Victoria, MN (US); and Joseph S. McGonigle, Minneapolis, MN (US)
Assigned to Surmodics, Inc., Eden Prairie, MN (US)
Filed by Surmodics, Inc., Eden Prairie, MN (US)
Filed on May 10, 2021, as Appl. No. 17/316,244.
Application 17/316,244 is a continuation of application No. 14/148,339, filed on Jan. 6, 2014, granted, now 11,000,632.
Claims priority of provisional application 61/783,179, filed on Mar. 14, 2013.
Claims priority of provisional application 61/748,859, filed on Jan. 4, 2013.
Prior Publication US 2021/0260255 A1, Aug. 26, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 29/14 (2006.01); A61L 29/04 (2006.01); A61L 29/08 (2006.01); B05D 7/00 (2006.01); C10M 107/28 (2006.01); C10M 107/42 (2006.01); C10M 107/46 (2006.01); C10M 107/48 (2006.01); C10M 107/50 (2006.01); C10M 135/36 (2006.01); C10M 169/04 (2006.01); C10M 177/00 (2006.01); C10N 20/00 (2006.01); C10N 50/00 (2006.01)
CPC A61L 29/14 (2013.01) [A61L 29/041 (2013.01); A61L 29/085 (2013.01); B05D 7/54 (2013.01); C10M 107/28 (2013.01); C10M 107/42 (2013.01); C10M 107/46 (2013.01); C10M 107/48 (2013.01); C10M 107/50 (2013.01); C10M 135/36 (2013.01); C10M 169/04 (2013.01); C10M 177/00 (2013.01); A61L 2400/10 (2013.01); A61L 2420/02 (2013.01); A61L 2420/08 (2013.01); C10M 2209/084 (2013.01); C10M 2209/0845 (2013.01); C10M 2217/0245 (2013.01); C10M 2217/0285 (2013.01); C10N 2020/01 (2020.05); C10N 2050/023 (2020.05); C10N 2050/025 (2020.05); Y10T 428/31573 (2015.04); Y10T 428/31699 (2015.04); Y10T 428/3175 (2015.04); Y10T 428/31928 (2015.04)] 17 Claims
 
1. A lubricious coating comprising:
a first coated layer comprising a vinyl pyrrolidone polymer and photoreactive groups, wherein the photoreactive groups are pendent from the vinyl pyrrolidone polymer or on a first cross-linking agent comprising at least two photoreactive groups, or both; and
a second coated layer that is different in composition than the first coated layer and is a top coating comprising an acid polymer, wherein the second coated layer is in direct contact with the first coated layer, wherein the first coated layer is between the second coated layer and a substrate surface,
wherein (a) the acid polymer is formed from a composition comprising one or more of the following monomers: acrylic acid, methacrylic acid, itaconic acid, monomethyl itaconic acid, maleic anhydride, fumaric acid, crotonic acid, acrylamido-2-methylpropanesulfonic acid (AMPS), 2-(meth)acrylamido-2-methylpropane sulfonic acid, vinyl sulfonic acid, 2-sulfoethyl methacrylate, and salts thereof, or (b) the acid polymer is a sulfonic acid polymer, a carboxylic acid polymer, or a phosphonic acid polymer.