US 12,409,252 B2
Settable surgical implants and their packaging
John Pacifico, Greenwich, CT (US); Aniq Darr, Riverdale, NY (US); and Richard L. Kronenthal, Fair Lawn, NJ (US)
Assigned to Abyrx, Inc., Stamford, CT (US)
Filed by Abyrx, Inc., Irvington, NY (US)
Filed on Aug. 16, 2022, as Appl. No. 17/820,003.
Application 17/820,003 is a continuation of application No. 16/668,595, filed on Oct. 30, 2019, granted, now 11,426,493.
Application 16/668,595 is a continuation of application No. 15/673,692, filed on Aug. 10, 2017, granted, now 10,517,998, issued on Dec. 31, 2019.
Application 15/673,692 is a continuation of application No. 14/553,847, filed on Nov. 25, 2014, granted, now 9,827,349, issued on Nov. 28, 2017.
Claims priority of provisional application 61/909,140, filed on Nov. 26, 2013.
Prior Publication US 2023/0191004 A1, Jun. 22, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 27/54 (2006.01); A61L 27/18 (2006.01); A61L 27/44 (2006.01); A61L 27/46 (2006.01); A61L 27/48 (2006.01); A61L 27/58 (2006.01)
CPC A61L 27/54 (2013.01) [A61L 27/18 (2013.01); A61L 27/446 (2013.01); A61L 27/46 (2013.01); A61L 27/48 (2013.01); A61L 27/58 (2013.01); A61L 2300/402 (2013.01); A61L 2300/404 (2013.01); A61L 2300/41 (2013.01); A61L 2300/414 (2013.01); A61L 2300/442 (2013.01); A61L 2400/06 (2013.01); A61L 2430/02 (2013.01)] 25 Claims
 
1. A package comprising one or more of a plurality of settable compositions, each composition consisting of a set of two reactive putties, A and B, the putties of the set each comprising amounts of reagents which, upon mixing together, react and cure into a final hardened form selected from the group consisting of a polyurethane, a polyureaurethane, a polyetherurethane, and a polyesterurethane, over a period of time at room or body temperature, each putty being physically separated from the other putty of its set within the package, and optionally, from other sets of putties,
wherein putty A comprises 15-40% of a first isocyanate component, 0.5-5% of a first polyol or polyamine component, and 5-85% of a first particulate material, based upon total weight of putty A; and putty B comprises 1-10% of a second isocyanate component, 3-15% of a second polyol or polyamine component, and 5-85% of a second particulate material, based upon total weight of putty B.