US 12,409,064 B2
Method and apparatus for suprachoroidal administration of therapeutic agent
Brendan J. Oberkircher, Cincinnati, OH (US); Daniel W. Price, Loveland, OH (US); Michael F. Keane, Downingtown, PA (US); Saeed Sokhanvar, Belmont, MA (US); Daniel J. Yasevac, Somerville, MA (US); Michel G. Bruehwiler, Newton, MA (US); Leah R. Soffer, Somerville, MA (US); Isaac J. Khan, Bridgewater, NJ (US); Benjamin L. Ko, Cincinnati, OH (US); Christopher D. Riemann, Cincinnati, OH (US); and Nathan D. Grubbs, West Chester, OH (US)
Assigned to Genentech, Inc., South San Francisco, CA (US)
Filed by Genentech, Inc., South San Francisco, CA (US)
Filed on Apr. 17, 2024, as Appl. No. 18/637,830.
Application 16/184,221 is a division of application No. 14/619,256, filed on Feb. 11, 2015, granted, now 10,226,379, issued on Mar. 12, 2019.
Application 18/637,830 is a continuation of application No. 17/346,654, filed on Jun. 14, 2021, granted, now 11,998,482.
Application 17/346,654 is a continuation of application No. 16/184,221, filed on Nov. 8, 2018, granted, now 11,058,576, issued on Jul. 13, 2021.
Claims priority of provisional application 62/104,295, filed on Jan. 16, 2015.
Claims priority of provisional application 62/049,128, filed on Sep. 11, 2014.
Claims priority of provisional application 62/049,089, filed on Sep. 11, 2014.
Claims priority of provisional application 62/049,100, filed on Sep. 11, 2014.
Claims priority of provisional application 62/049,056, filed on Sep. 11, 2014.
Claims priority of provisional application 61/938,956, filed on Feb. 12, 2014.
Prior Publication US 2024/0277518 A1, Aug. 22, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 9/00 (2006.01); A61M 5/158 (2006.01)
CPC A61F 9/0017 (2013.01) [A61F 9/0008 (2013.01); A61M 5/158 (2013.01); A61M 2005/1585 (2013.01); A61M 2210/0612 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
(a) a body;
(b) a cannula extending distally from the body, wherein the cannula is flexible, wherein the cannula has an atraumatic distal end, wherein the cannula defines a lumen extending distally toward the atraumatic distal end, wherein the cannula is sized and configured to pass between a sclera layer and a choroid layer in a human eye, wherein the atraumatic distal end is configured to provide separation between the choroid layer and the sclera layer during advancement of the cannula between the choroid layer and the sclera layer;
(c) a needle slidably disposed within the lumen;
(d) a conduit in fluid communication with the needle; and
(e) a first magnetic element positioned in the body.