US 12,409,024 B2
Flow modification devices in body lumens
Sagy Karavany, Kibbutz Dvir (IL); Oren Moshe Rotman, Holon (IL); Eyal Teichman, Hod-Hasharon (IL); Tanhum Feld, Moshav Merhavya (IL); Menashe Yacoby, Shoham (IL); and Boaz Nishri, Maagan Michael (IL)
Assigned to Nephronyx Ltd., Modiin (IL)
Appl. No. 17/296,199
Filed by Nephronyx Ltd., Modiin (IL)
PCT Filed Nov. 25, 2019, PCT No. PCT/IB2019/060142
§ 371(c)(1), (2) Date May 21, 2021,
PCT Pub. No. WO2020/109979, PCT Pub. Date Jun. 4, 2020.
Claims priority of provisional application 62/873,755, filed on Jul. 12, 2019.
Claims priority of provisional application 62/771,559, filed on Nov. 26, 2018.
Prior Publication US 2022/0039938 A1, Feb. 10, 2022
Int. Cl. A61F 2/06 (2013.01); A61F 2/966 (2013.01); A61M 60/135 (2021.01); A61M 60/216 (2021.01)
CPC A61F 2/06 (2013.01) [A61F 2/966 (2013.01); A61M 60/135 (2021.01); A61M 60/216 (2021.01); A61F 2002/068 (2013.01); A61F 2250/0039 (2013.01)] 28 Claims
OG exemplary drawing
 
1. A device for altering fluid flow through a body lumen, the body lumen coupled to a branch lumen, the device comprising:
a flow modulator configured to be positioned within the body lumen, the flow modulator comprising an upstream component, a downstream component, and an entrainment region, the upstream component having an inlet, an outlet, and a cross-sectional flow area that converges from the inlet towards the outlet, the downstream component having an entry, an exit, and a cross-sectional flow area that diverges from the entry towards the exit, and the entrainment region comprising a diverging portion and a plurality of longitudinally extending openings radially spaced around the diverging portion of the entrainment region, the entrainment region between the inlet of the upstream component and the exit of the downstream component,
wherein the flow modulator is configured to accelerate a fluid stream passing through the upstream component towards the downstream component to generate a low pressure region in the vicinity of the entrainment region that entrains additional fluid into the fluid stream via the plurality of longitudinally extending openings as the fluid stream passes into the entry of the downstream component.