| CPC A61F 2/013 (2013.01) [A61F 2/011 (2020.05)] | 20 Claims |

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1. An embolic protection system for isolating a cerebral vasculature, the system comprising:
an outer sheath, having a proximal end and a distal end;
an inner member extending through and slidable within a lumen of the outer sheath;
a distal anchoring mechanism fixed to a distal end region of the inner member;
a proximal filter membrane carried between the inner member and the outer sheath, the proximal filter membrane extending proximally from the distal anchoring mechanism and configured to extend from a left subclavian artery to a brachiocephalic artery;
an aortic ring coupled to the proximal filter membrane and configured to seal the proximal filter membrane against a wall of an aorta; and
a handle including a first actuation mechanism coupled to a proximal end of the inner member, wherein the first actuation mechanism is configured to retract the inner member proximally relative to the proximal filter membrane, pulling the inner member up against a roof of an aortic arch.
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