| CPC A61B 18/1492 (2013.01) [A61B 34/20 (2016.02); A61B 2018/0022 (2013.01); A61B 2018/00541 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00875 (2013.01); A61B 2018/00982 (2013.01); A61B 2018/048 (2013.01); A61B 2018/1425 (2013.01); A61B 2018/1467 (2013.01); A61B 2018/1472 (2013.01); A61B 2034/2051 (2016.02); A61B 2034/2061 (2016.02); A61B 2034/2063 (2016.02); A61B 2218/002 (2013.01); A61B 2218/007 (2013.01)] | 32 Claims |

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1. A method to treat a human patient comprising:
advancing a catheter through a natural airway of the patient and positioning a distal portion of the catheter in the natural airway of a lung of the patient at a target region in the lung,
injecting a conductive hypertonic saline solution having a concentration of at least 5% of sodium chloride by weight/volume from the distal portion of the catheter into the target region, wherein the injecting of the conductive hypertonic saline solution injects no more than 20 ml of the conductive hypertonic saline solution into the target region;
delivering energy from the distal portion into the conductive hypertonic saline solution in the target region, wherein the energy heats the conductive hypertonic saline solution in the portion of the airway, and
ablating the target region with the energy delivered from the distal portion.
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