US 12,408,977 B2
Methods for monitoring ablation progress with doppler ultrasound
Jiayu Chen, Palo Alto, CA (US)
Assigned to Gynesonics, Inc., Redwood City, CA (US)
Filed by Gynesonics, Inc., Redwood City, CA (US)
Filed on Feb. 22, 2023, as Appl. No. 18/173,000.
Application 18/173,000 is a continuation of application No. 16/666,271, filed on Oct. 28, 2019, granted, now 11,612,431.
Application 16/666,271 is a continuation of application No. PCT/US2018/030295, filed on Apr. 30, 2018.
Claims priority of provisional application 62/501,238, filed on May 4, 2017.
Prior Publication US 2024/0024023 A1, Jan. 25, 2024
Int. Cl. A61B 18/14 (2006.01); A61B 90/00 (2016.01); A61B 18/00 (2006.01)
CPC A61B 18/1492 (2013.01) [A61B 18/1477 (2013.01); A61B 90/37 (2016.02); A61B 2018/00577 (2013.01); A61B 2018/143 (2013.01); A61B 2090/378 (2016.02)] 20 Claims
OG exemplary drawing
 
1. A system for treating a target tissue, the system comprising:
a treatment probe comprising a handle, a probe body, an imaging source coupled to the probe body, and an ablation element coupled to the probe body and configured to ablate the target tissue;
a real-time display coupled to the treatment probe; and
a controller coupled to the imaging source of the treatment probe and the real-time display, the controller comprising a computer readable, non-transient storage medium comprising:
(i) instructions for the imaging source to generate a real-time image of the target tissue during ablation of the target tissue,
(ii) instructions for the real-time display to display the real-time image, the real-time image showing the target tissue and a virtual treatment boundary around the target tissue,
(iii) instructions for determining an initial blood perfusion of the target tissue,
(iv) instructions for, prior to initiating ablation of the target tissue, modifying one or more of a size or location of the virtual treatment boundary based on the determined initial blood perfusion of the target tissue, and
(v) instructions for determining a real-time blood perfusion level within the virtual treatment boundary, and determining a completion percentage of the ablation of the target tissue within the virtual treatment boundary based on the determined real-time blood perfusion level within the virtual treatment boundary, thereby indicating to a user a progress of the ablation of the target tissue.