| CPC A61B 18/1477 (2013.01) [A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/124 (2013.01); A61B 2018/1467 (2013.01); A61B 2034/252 (2016.02); A61B 2034/254 (2016.02)] | 19 Claims |

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1. A method of treating infected tissue of a patient comprising:
placing at least one electrode near a treatment site that comprises the infected tissue;
activating a generator to generate electrical pulses through the at least one electrode;
wherein the electrical pulses are sufficient to non-thermally ablate the infected tissue while leaving intact a natural tissue scaffold of the patient within the treatment site;
wherein the treatment site further comprises a pre-placed return electrode, wherein the pre-placed return electrode includes a medical device having a conductive material.
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