US 12,408,884 B2
System and method for X-ray elastography using dynamic pulsing
Rajiv Gupta, Wayland, MA (US); Chika Kamezawa, Boston, MA (US); Avilash Cramer, Cambridge, MA (US); Wolfgang Krull, Boxford, MA (US); Wataru Yashiro, Boston, MA (US); and Kazuyuki Hyodo, Boston, MA (US)
Assigned to The General Hospital Corporation, Boston, MA (US)
Filed by The General Hospital Corporation, Boston, MA (US)
Filed on Dec. 16, 2022, as Appl. No. 18/067,517.
Claims priority of provisional application 63/290,609, filed on Dec. 16, 2021.
Prior Publication US 2023/0190214 A1, Jun. 22, 2023
Int. Cl. A61B 6/00 (2024.01); A61B 6/46 (2024.01)
CPC A61B 6/486 (2013.01) [A61B 6/461 (2013.01); A61B 6/5217 (2013.01); A61B 6/5258 (2013.01); A61B 6/542 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method for performing dynamic X-ray elastography, the method comprising:
controlling a vibration source to generate shear waves in a region of interest of a subject;
controlling an X-ray source to direct a series of X-ray pulses, pulsed at a predetermined frequency, toward the region of interest of the subject, wherein the predetermined frequency is synchronized to a selected phase of the shear waves;
detecting the X-ray pulses using an X-ray detector to acquire X-ray data;
generating, using a processor, stiffness maps from the X-ray data; and
displaying, using a display, the stiffness maps.