US 12,079,958 B2
Method of and apparatus for creating an all-in-focus image of a portion of an iridocorneal angle of an eye
Andrea Peroni, Venice (IT); Andrea De Giusti, Padua (IT); Michele Pascolini, Padua (IT); Mattia Minozzi, Legnaro (IT); and Simone Pajaro, Padua (IT)
Assigned to NIDEK CO., LTD., Aichi (JP)
Appl. No. 17/602,622
Filed by NIDEK CO. LTD., Aichi (JP)
PCT Filed Apr. 15, 2020, PCT No. PCT/IB2020/053546
§ 371(c)(1), (2) Date Oct. 8, 2021,
PCT Pub. No. WO2020/212861, PCT Pub. Date Oct. 22, 2020.
Claims priority of application No. 102019000006124 (IT), filed on Apr. 19, 2019.
Prior Publication US 2022/0198630 A1, Jun. 23, 2022
Int. Cl. G06T 7/13 (2017.01); G06T 5/50 (2006.01); G06T 5/70 (2024.01); G06T 5/90 (2024.01); G06T 7/30 (2017.01)
CPC G06T 5/50 (2013.01) [G06T 5/70 (2024.01); G06T 5/90 (2024.01); G06T 7/13 (2017.01); G06T 7/30 (2017.01); G06T 2207/20028 (2013.01); G06T 2207/30041 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method of creating an all-in-focus image of a portion of an iridocorneal angle of an eye starting from a plurality of images, the images of said plurality being shallow field-depth images of said portion taken with different focus planes and with a same image frame, the method comprising the steps of:
A) pre-processing said plurality of images so to obtain a plurality of single-channel images if the images of said plurality are color images,
B) calculating an initial focus map starting from said plurality of single-channel images,
C) creating an initial estimated all-in-focus image starting from said initial focus map and said plurality of single-channel images,
D) calculating an initial edge map starting from said initial focus map and said plurality of single-channel images,
E) iterating a regularization process until a stop-regularization condition is met, wherein the regularization process comprises removing one or more edge points of the initial edge map by considering a reference model of an iridocorneal angle of an eye, and
F) creating said all-in-focus image starting from said plurality of images and a focus map last calculated in step E;
wherein in step E said reference model expresses a first parameter being a maximum inclination of a surface of an iridocorneal angle of an eye and/or a second parameter being a direction of maximum inclination of a surface of an iridocorneal angle of an eye and/or a third parameter being a direction of minimum inclination of a surface of an iridocorneal angle of an eye.