US 12,078,631 B2
Sample analysis apparatus and sample analysis method
Fangang Kong, Shenzhen (CN); Xinjun Zhang, Shenzhen (CN); Weiwei Yan, Shenzhen (CN); and Shaojian Liu, Shenzhen (CN)
Assigned to Shenzhen Mindray Animal Medical Technology Co., Ltd., Shenzhen (CN)
Filed by Shenzhen Mindray Animal Medical Technology Co., Ltd., Guangdong (CN)
Filed on Dec. 29, 2022, as Appl. No. 18/091,220.
Application 18/091,220 is a continuation of application No. PCT/CN2021/115674, filed on Aug. 31, 2021.
Prior Publication US 2023/0143409 A1, May 11, 2023
Int. Cl. G01N 33/50 (2006.01); G01N 35/00 (2006.01); G01N 35/10 (2006.01); G01N 15/01 (2024.01)
CPC G01N 33/5005 (2013.01) [G01N 35/00584 (2013.01); G01N 35/1002 (2013.01); G01N 2015/016 (2024.01); G01N 2035/00851 (2013.01); G01N 2035/00891 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A sample analysis apparatus, the sample analysis apparatus being configured to analyze samples of one or more animals; the sample analysis apparatus comprising:
a sample supply portion configured to supply a sample to be tested including
(a) a blood sample or
(b) a body fluid sample to be tested;
a reagent supply portion configured to supply a reagent;
a reaction portion configured to provide a reaction place for the sample to be tested and the reagent so as to prepare a test sample formed by reaction of the sample to be tested and the reagent;
a detection portion configured to detect the test sample so as to obtain detection data; and
a processor configured to calculate a detection result according to the detection data from
(a) a plurality of leukocyte measurement modes for the blood sample of at least one of the one or more animals, wherein each of the leukocyte measurement modes for the blood sample comprises a reaction time and different leukocyte measurement modes for the blood sample of a single animal having different reaction times, or
(b) a plurality of leukocyte measurement modes for the body fluid sample of at least one of the one or more animals, wherein each of the leukocyte measurement modes for the body fluid sample comprises a reaction time and different leukocyte measurement modes for the body fluid sample of a single animal having different reaction times; wherein the processor obtains a current leukocyte measurement mode for the sample of the single animal to be tested;
the processor controls the sample supply portion to provide the sample to be tested to the reaction portion, and controls the reagent supply portion to provide the reagent containing a hemolytic agent to the reaction portion;
the processor controls the sample to be tested and the reagent to react in the reaction portion according to the reaction time set in the current leukocyte measurement mode for the sample to be tested, so as to prepare the test sample for detecting leukocytes;
the processor controls the detection portion to detect the test sample so as to obtain detection data of leukocyte classification and the processor processes the detection data to obtain a detection result of the leukocyte classification; and
the processor determines whether erythrocyte fragments in the test sample interfere with the detection result of leukocyte classification according to the detection data of leukocyte classification; and
upon determining the erythrocyte fragments are interfering, the processor controls to send out a prompt to an interface for a user that the erythrocyte fragments interfere with the detection result of leukocyte classification, and/or controls to send out a prompt to an interface for a user to switch the leukocyte measurement mode.