US 12,078,576 B2
Devices and methods for laser capture microdissection
Joel Colburn, Foster City, CA (US); Mousumi Rath, San Ramon, CA (US); and Sarah Ghanbari, Placentia, CA (US)
Assigned to Life Technologies Corporation, Carlsbad, CA (US)
Filed by LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US)
Filed on Jan. 29, 2021, as Appl. No. 17/162,034.
Application 17/162,034 is a continuation of application No. 16/222,933, filed on Dec. 17, 2018, granted, now 10,921,218.
Application 16/222,933 is a continuation of application No. 15/233,756, filed on Aug. 10, 2016, abandoned.
Claims priority of provisional application 62/341,563, filed on May 25, 2016.
Claims priority of provisional application 62/303,227, filed on Mar. 3, 2016.
Claims priority of provisional application 62/203,311, filed on Aug. 10, 2015.
Prior Publication US 2021/0148792 A1, May 20, 2021
Int. Cl. G01N 1/04 (2006.01); B01L 3/00 (2006.01); C12Q 1/6806 (2018.01); G01N 1/02 (2006.01); G01N 1/28 (2006.01); G01N 1/34 (2006.01)
CPC G01N 1/04 (2013.01) [C12Q 1/6806 (2013.01); G01N 1/2813 (2013.01); G01N 1/286 (2013.01); B01L 3/50825 (2013.01); B01L 2300/042 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0838 (2013.01); G01N 2001/028 (2013.01); G01N 2001/045 (2013.01); G01N 2001/284 (2013.01); G01N 2001/2886 (2013.01); G01N 1/34 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A sample carrier, comprising:
a cap formed from a substrate with a body disposed about an axis orthogonal to a top surface and a bottom surface of the substrate, said cap including:
an upper portion of the substrate body comprising an outer perimeter, a first shoulder, and the top surface;
an intermediate portion of the substrate body, wherein the intermediate portion comprises a first seating area with a first diameter configured to provide an interference fit within a first-sized sample chamber opening and a second shoulder;
a lower portion of the substrate body, wherein the lower portion comprises a second seating area with a second diameter configured to provide an interference fit within a second-sized sample chamber opening and the bottom surface;
wherein the outer perimeter of the upper portion is larger than the first diameter of the first seating area of the intermediate portion, and wherein the first diameter is larger than the second diameter of the second seating area of the lower portion; and
a sample transfer film applied to the bottom surface of the cap.