US 12,078,539 B2
Single photon counting flow cytometer
Masanobu Yamamoto, West Lafayette, IN (US); Keegan Hernandez, West Lafayette, IN (US); and J. Paul Robinson, West Lafayette, IN (US)
Assigned to MIFTEK CORPORATION, West Lafayette, IN (US)
Filed by MIFTEK CORPORATION, West Lafayette, IN (US)
Filed on Sep. 29, 2023, as Appl. No. 18/375,404.
Application 18/375,404 is a continuation of application No. 17/536,068, filed on Nov. 28, 2021, granted, now 11,781,912.
Application 17/536,068 is a continuation of application No. 16/604,557, granted, now 11,187,584, issued on Nov. 30, 2021, previously published as PCT/US2018/027302, filed on Apr. 12, 2018.
Claims priority of provisional application 62/485,207, filed on Apr. 13, 2017.
Prior Publication US 2024/0027270 A1, Jan. 25, 2024
Int. Cl. G01J 3/44 (2006.01); G01J 3/02 (2006.01)
CPC G01J 3/4406 (2013.01) [G01J 3/0218 (2013.01); G01J 3/0227 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A measurement system, comprising:
a flow chamber configured to propagate a sample in a flow stream;
one or more optical sources configured to irradiate the sample in the flow stream;
one or more detector systems each configured to receive resultant light from the sample and, in response, generate a photon signal, the one or more detector systems each including one or more photon sensors each adapted to generate an electronic pulse in response to receiving a photon and a circuit operating in the giga hertz supporting the one or more photon sensors thus configured to count each individual photon in the resultant light from the sample.