	US 12,078,537 B2
	System and method for finding the peak wavelength of the spectrum sensed by an LSPR spectrometer
Udayan Kanade, Pune (IN); and Sanat Ganu, Pune (IN)
Assigned to Nicoya Lifesciences Inc., Kitchener (CA)
Appl. No. 18/549,489
Filed by Nicoya Lifesciences Inc., Kitchener (CA)
PCT Filed Mar. 1, 2022, PCT No. PCT/CA2022/050291 § 371(c)(1), (2) Date Sep. 7, 2023, PCT Pub. No. WO2022/187931, PCT Pub. Date Sep. 15, 2022.
Claims priority of provisional application 63/158,214, filed on Mar. 8, 2021.
Prior Publication US 2024/0175749 A1, May 30, 2024
Int. Cl. G01J 3/28 (2006.01); G01N 21/552 (2014.01)

CPC G01J 3/28 (2013.01) [G01N 21/554 (2013.01); G01J 2003/2859 (2013.01)]

19 Claims

1. A method for finding a peak wavelength of a spectrum sensed by a spectrometer comprising:

providing a sample comprising an analyte;

analyzing the analyte using SPR analysis to produce a signal;

using an imaging device to measure and store data from the signal, thereby yielding stored image data; and

using a computer to:

estimate from the stored image data a model spectrum representing an absorbance or reflectance spectrum;

estimate from the model spectrum a mathematical modeling function comprising a parametric curve representing the absorbance/reflectance spectrum; and

adjust parameters of the parametric curve thereby increasing the likelihood of the model spectrum representing the spectrum sensed by the spectrometer.