| CPC C12P 7/04 (2013.01) [C12M 29/06 (2013.01); C12M 29/18 (2013.01); C12M 29/24 (2013.01)] | 13 Claims |
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1. A bioreactor system comprising:
(i) a riser section;
(ii) a downcomer section, containing fermentation broth, in fluid communication with the riser section;
(iii) at least two liquid distributors each comprising a circular pipe conduit longitudinally extending from a wall of the downcomer section and terminating at a closed end proximate to a center vertical axis of the downcomer section; and
(iv) the circular pipe conduit of each distributor comprising:
a plurality of liquid injection apertures along each of the circular pipe conduit beginning at a proximal end from the center vertical axis and terminating at a distal end from the center vertical axis;
(v) the liquid injection apertures, of each circular pipe conduit, arranged such that the spacing between successive apertures decreases non-uniformly along the length of the circular pipe conduit from the proximal end of the center vertical axis of the downer section to the distal end of the center vertical axis of the downer section; and
(vi) wherein the liquid injection apertures, on each distributor, alternate and are offset between a top and a bottom surface of the circular pipe conduit.
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