CPC C12N 7/00 (2013.01) [C12N 1/06 (2013.01); C12N 15/86 (2013.01); C12N 2750/14041 (2013.01); C12N 2750/14152 (2013.01)] | 20 Claims |
1. An adeno-associated virus (AAV) production system, comprising:
(a) mammalian cells adapted for suspension culture;
(b) an AAV transfer vector;
(c) one or more packaging plasmids;
(d) an enhancer comprising one or more histone deacetylase (HDAC) inhibitor; and
(e) cell culture media that supports growth and expansion of the mammalian cells.
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