US 12,077,574 B2
Methods and composition for neutralization of influenza
Patrick Wilson, Chicago, IL (US); Yaoqing Chen, Chicago, IL (US); and Haley L. Dugan, Chicago, IL (US)
Assigned to The University of Chicago, Chicago, IL (US)
Filed by The University of Chicago, Chicago, IL (US)
Filed on Jun. 15, 2023, as Appl. No. 18/335,876.
Application 18/335,876 is a division of application No. 16/977,327, granted, now 11,702,464, previously published as PCT/US2019/020223, filed on Mar. 1, 2019.
Claims priority of provisional application 62/637,508, filed on Mar. 2, 2018.
Prior Publication US 2024/0117016 A1, Apr. 11, 2024
Int. Cl. C07K 16/10 (2006.01); A61K 39/42 (2006.01); A61K 45/06 (2006.01); A61P 31/16 (2006.01); A61K 39/00 (2006.01)
CPC C07K 16/1018 (2013.01) [A61K 39/42 (2013.01); A61K 45/06 (2013.01); A61P 31/16 (2018.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01)] 10 Claims
 
1. An antibody or antibody fragment comprising a heavy chain variable region comprising a CDR1 of SEQ ID NO: 68, a CDR2 of SEQ ID NO: 70 and CDR3 of SEQ ID NO: 72, and a light chain variable region comprising a CDR1 of SEQ ID NO: 76, a CDR2 of SEQ ID NO: 78 and CDR3 of SEQ ID NO: 80 wherein the antibody or antibody fragment is capable of binding to influenza neuraminidase (NA) protein.