US 12,076,527 B2
Method and apparatus for a long-term, fully implantable MRI compatible drug pump
Yehoshua Shachar, Santa Monica, CA (US); and Winston Wu, Alhambra, CA (US)
Assigned to Cognos Therapeutics Inc., Inglewood, CA (US)
Filed by Cognos Therapeutics Inc., Los Angeles, CA (US)
Filed on Apr. 29, 2019, as Appl. No. 16/397,623.
Prior Publication US 2020/0338325 A1, Oct. 29, 2020
Int. Cl. A61M 5/142 (2006.01); A61M 5/168 (2006.01); A61M 5/172 (2006.01); A61M 27/00 (2006.01)
CPC A61M 5/14276 (2013.01) [A61M 5/16831 (2013.01); A61M 5/16881 (2013.01); A61M 5/172 (2013.01); A61M 27/002 (2013.01); A61M 2005/14208 (2013.01); A61M 2005/16863 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/3344 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/3553 (2013.01); A61M 2205/3584 (2013.01); A61M 2205/50 (2013.01); A61M 2205/52 (2013.01); A61M 2205/7518 (2013.01)] 27 Claims
OG exemplary drawing
 
1. An magnetic resonance imaging (MRI) compatible apparatus comprising:
a refillable drug reservoir;
a hermetically sealed, implantable chamber defined between a fluidic plate and a cap;
a pump hermetically sealed to the fluidic plate and fluidically communicated to the drug reservoir;
control electronics coupled to a mid layer disposed within the hermetically sealed, implantable chamber, the control electronics electrically communicated to the pump; and
a refill inlet, a pressure sensor, and an outlet clog sensor, where each of the refill inlet, the pressure sensor, and the outlet clog sensor are coupled to the fluidic plate,
where the mid layer comprises a plurality of holes defined therein, where each of the plurality of holes accommodate a respective one of the refill inlet, the pressure sensor, and the outlet clog sensor,
where the pressure sensor and the outlet clog sensor are electrically communicated to the control electronics coupled to the mid layer, and
where the refillable drug reservoir, the hermetically sealed, implantable chamber, the pump and the control electronics are MRI compatible.