US 12,076,481 B2
Medicament delivery device
David Cottenden, Royston (GB); Jianye Wang, Royston (GB); Duncan Young, Royston (GB); Desmond Cheung, Royston (GB); Simon Waddelow, Royston (GB); Iain McDerment, Royston (GB); Rob Selby, Royston (GB); Catherine Wyman, Royston (GB); Rob May, Royston (GB); and Chris Groombridge, Royston (GB)
Assigned to TTP PLC, Royston (GB)
Appl. No. 17/273,203
Filed by TTP PLC, Royston (GB)
PCT Filed Sep. 3, 2019, PCT No. PCT/GB2019/052452
§ 371(c)(1), (2) Date Mar. 3, 2021,
PCT Pub. No. WO2020/049289, PCT Pub. Date Mar. 12, 2020.
Claims priority of application No. 1814300 (GB), filed on Sep. 3, 2018; and application No. 1905545 (GB), filed on Apr. 18, 2019.
Prior Publication US 2021/0322686 A1, Oct. 21, 2021
Int. Cl. A61M 15/00 (2006.01)
CPC A61M 15/0051 (2014.02) [A61M 15/0055 (2014.02); A61M 2202/064 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising:
at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of the medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position,
wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of said opened compartment,
wherein the opening mechanism further comprises a cylindrical indexing wheel having a plurality of indentations spaced around its exterior surface, each indentation from the plurality of indentations configured to receive a compartment from the plurality of individual compartments of the medicament carrier therein such that rotation of the indexing wheel advances the medicament carrier and thereby moves the plurality of individual compartments of the medicament carrier sequentially into the entrainment position, and
wherein the indexing wheel has an axial through-bore arranged to be in fluid communication with a side of said surface of the release member arranged to face the carrier strip such that the indexing wheel and the release member thereby form part of an entrainment airpath.