US 12,076,472 B2
Systems and methods for monitoring fluid volumes during peritoneal dialysis
Peter Kotanko, New York, NY (US); and Fansan Zhu, Flushing, NY (US)
Assigned to FRESENIUS MEDICAL CARE HOLDINGS, INC., Waltham, MA (US)
Filed by FRESENIUS MEDICAL CARE HOLDINGS, INC., Waltham, MA (US)
Filed on Oct. 9, 2020, as Appl. No. 17/066,554.
Claims priority of provisional application 62/913,217, filed on Oct. 10, 2019.
Prior Publication US 2021/0106741 A1, Apr. 15, 2021
Int. Cl. A61M 1/28 (2006.01); G16H 20/17 (2018.01); G16H 20/40 (2018.01); G16H 40/63 (2018.01); A61B 5/03 (2006.01)
CPC A61M 1/282 (2014.02) [G16H 20/17 (2018.01); G16H 20/40 (2018.01); G16H 40/63 (2018.01); A61B 5/03 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/52 (2013.01); A61M 2209/088 (2013.01); A61M 2210/1017 (2013.01); A61M 2210/1021 (2013.01); A61M 2230/65 (2013.01)] 10 Claims
OG exemplary drawing
 
1. One or more non-transitory computer-readable media storing instructions that, when executed by one or more processors, cause the one or more processors to perform operations comprising:
computing a plurality of lower abdominal fluid volumes, continuously during a dwell time of a peritoneal dialysis treatment, based at least on bioimpedance data from a first plurality of electrodes positioned on a patient's upper thighs;
computing a plurality of intraperitoneal volumes, continuously during the dwell time of the peritoneal dialysis treatment, based at least on the bioimpedance data from the first plurality of electrodes and bioimpedance data from a second plurality of electrodes positioned on the patient's torso; and
controlling operation of a pump of a peritoneal dialysis device to maximize ultrafiltration volume, based at least on one or more of the plurality of lower abdominal fluid volumes and one or more of the plurality of intraperitoneal volumes, wherein computing the peritoneal volumes comprises applying bioimpedance data from the first plurality of electrodes to an electrical circuit model that is based at least in part on (a) a first resistance between a first electrode in the first plurality of electrodes and a second electrode in the second plurality of electrodes in parallel with (b) a second resistance between a third electrode in the first plurality of electrodes and a fourth electrode in the second plurality of electrodes.