US 12,076,424 B2
Glass composition
Daniel Boyd, Upper Tantallon (CA); Kathleen O′Connell, Halifax (CA); and Kathleen Naomi MacDonald-Parsons, Bedford (CA)
Assigned to IR SCIENTIFIC INC., Halifax (CA)
Appl. No. 17/273,661
Filed by IR Scientific Inc., Halifax (CA)
PCT Filed Sep. 4, 2019, PCT No. PCT/CA2019/051237
§ 371(c)(1), (2) Date Mar. 4, 2021,
PCT Pub. No. WO2020/047662, PCT Pub. Date Mar. 12, 2020.
Claims priority of provisional application 62/847,807, filed on May 14, 2019.
Claims priority of provisional application 62/727,377, filed on Sep. 5, 2018.
Prior Publication US 2021/0259933 A1, Aug. 26, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/21 (2006.01); A61K 6/30 (2020.01); A61K 8/04 (2006.01); A61K 8/27 (2006.01); A61Q 11/00 (2006.01); C03C 3/14 (2006.01); C03C 3/23 (2006.01); C03C 4/00 (2006.01); C03C 12/00 (2006.01)
CPC A61K 8/21 (2013.01) [A61K 6/30 (2020.01); A61K 8/042 (2013.01); A61K 8/27 (2013.01); A61Q 11/00 (2013.01); C03C 3/14 (2013.01); C03C 3/23 (2013.01); C03C 4/0021 (2013.01); C03C 12/00 (2013.01); C03C 2204/00 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A dentin-desensitizing composition comprising:
(i) glass particles that are from about 1 to about 50 um in size; and
(ii) a water-free, orally-compatible carrier;
wherein:
the glass particles lose at least 5 mass % within 24 hours when exposed to a buffered saline solution;
the composition of the glass particles consists of:
about 50 mol % B2O3,
about 15 mol % Na2O,
about 20 mol % MgO,
about 10 mol % CaO, and
about 5 mol % NaF, KF, CaF2, SnF2, or any combination thereof.