wherein:

R^2A is selected from —NR⁶-heteroaryl and —NR⁶-aryl each of which aryl or heteroaryl is optionally substituted with 1, 2, 3, or 4 substituents independently selected from the group consisting of alkyl, haloalkyl, —OR⁶, F, Cl, Br, —NR⁶R⁷, cyano, and C(O)R³;

R³ at each occurrence is independently selected from hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, arylalkyl, aryl, heteroaryl, heterocycle, —OR⁶, and —NR⁸R⁹;

R⁵ is independently selected from hydrogen, heteroalkyl, C₀-C₆alkyl-cyano, alkyl, alkenyl, alkynyl, F, Cl, Br, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocycle, heterocycloalkyl, haloalkoxy, —O-alkenyl, —O-alkynyl, C₀-C₆alkyl-OR⁶, C₀-C₆alkyl-SR⁶, C₀-C₆alkyl-NR⁶R⁷, C₀-C₆alkyl-C(O)R³, C₀-C₆alkyl-S(O)R³, C₀-C₆alkyl-C(S)R³, C₀-C₆alkyl-S(O)₂R³, C₀-C₆alkyl-N(R⁸)—C(O)R³, C₀-C₆alkyl-N(R⁸)—S(O)R³, C₀-C₆alkyl-N(R⁸)—S(O)₂R³, C₀-C₆alkyl-O—C(O)R³, C₀-C₆alkyl-O—S(O)R³, C₀-C₆alkylN₃, and C₀-C₆alkyl-O—S(O)₂R³, each of which is optionally substituted with 1, 2, 3, or 4 substituents independently selected from C₁-C₄alkyl, C₁-C₄haloalkyl, —OR⁶, F, Cl, Br, —NR⁶R⁷, cyano, nitro, and C(O)R³, wherein the optional substituent is selected such that a stable compound results;

R⁶ and R⁷ are independently selected at each occurrence from hydrogen, alkyl, arylalkyl, heteroarylalkyl, aryl, haloalkyl, heteroaryl, heterocycle, -alkyl-OR⁸, -alkyl-NR⁸R⁹, C(O)R³, S(O)R³, C(S)R³, and S(O)₂R³; and

R⁸ and R⁹ are independently selected at each occurrence from hydrogen, heteroalkyl, alkyl, arylalkyl, heteroarylalkyl, alkenyl, alkynyl, aryl, heteroaryl, and heterocycle.