US 12,076,356 B2
Composition comprising Molokhia extract as active ingredient for improving gut microbiome or for alleviating, preventing, or treating intestinal inflammation, leaky gut syndrome, obesity, or metabolic disease
Ho-Young Park, Jeollabuk-do (KR); Yoon-sook Kim, Seoul (KR); Young-do Nam, Jeollabuk-do (KR); Moon Ho Do, Gyeonggi-do (KR); Mi-Jin Oh, Jeollabuk-do (KR); Sang-hoon Lee, Jeollabuk-do (KR); Eun Jung Lee, Seoul (KR); Hye-Bin Lee, Jeollabuk-do (KR); and Hyun Jhung Jhun, Jeollabuk-do (KR)
Assigned to KOREA FOOD RESEARCH INSTITUTE, Jeollabuk-do (KR)
Appl. No. 17/282,820
Filed by KOREA FOOD RESEARCH INSTITUTE, Jeollabuk-do (KR)
PCT Filed Sep. 19, 2019, PCT No. PCT/KR2019/012175
§ 371(c)(1), (2) Date Apr. 5, 2021,
PCT Pub. No. WO2020/071667, PCT Pub. Date Apr. 9, 2020.
Claims priority of application No. 10-2018-0118793 (KR), filed on Oct. 5, 2018; application No. 10-2019-0038911 (KR), filed on Apr. 3, 2019; and application No. 10-2019-0048995 (KR), filed on Apr. 26, 2019.
Prior Publication US 2021/0353697 A1, Nov. 18, 2021
Int. Cl. A61K 36/185 (2006.01); A61P 1/00 (2006.01); A61P 1/14 (2006.01); A61P 3/04 (2006.01); A61P 29/00 (2006.01)
CPC A61K 36/185 (2013.01) [A61P 1/00 (2018.01); A61P 1/14 (2018.01); A61P 3/04 (2018.01); A61P 29/00 (2018.01)] 13 Claims
 
1. A method of treating a disease in a human in need thereof comprising administering to the human in need thereof a therapeutically effective amount of a Molokhia extract to effectively treat the disease in the human in need thereof, wherein the disease is selected from the group consisting of leaky gut syndrome, Crohn's disease, ulcerative colitis, chronic Behcet's disease, infectious enteritis, ischemic bowel disease and radiation enteritis.