US 12,076,355 B2
Composition and method for treating cancer
Tung-Yi Lin, Taipei (TW); and Mei-Kuang Lu, Taipei (TW)
Assigned to National Yang Ming Chiao Tung University, Taipei (TW); and National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei (TW)
Filed by National Yang Ming Chiao Tung University, Taipei (TW); and National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei (TW)
Filed on Nov. 23, 2022, as Appl. No. 17/993,343.
Claims priority of provisional application 63/283,420, filed on Nov. 26, 2021.
Prior Publication US 2023/0165917 A1, Jun. 1, 2023
Int. Cl. A61K 36/07 (2006.01); A61K 31/737 (2006.01); A61P 35/00 (2006.01)
CPC A61K 36/07 (2013.01) [A61K 31/737 (2013.01); A61P 35/00 (2018.01)] 15 Claims
 
1. A method for treating cancer, comprising administering to a subject in need thereof a composition comprising an effective amount of a fraction of polysaccharide isolated from Antrodia cinnamomea cultured in the presence of zinc sulfate and a pharmaceutical carrier thereof, wherein the polysaccharide comprises glucose and fucose;
wherein the polysaccharide is sulfated polysaccharide; and
wherein the cancer involves signal transduction through EGFR, TGFβRI or a combination thereof.