	US 12,076,333 B2
	Lysophosphatidylcholine compositions
Nils Hoem, Stamsund (NO); Finn Myhren, Stamsund (NO); Petter-Arnt Hals, Stamsund (NO); and Armend Håti, Stamsund (NO)
Assigned to AKER BIOMARINE HUMAN INGREDIENTS AS, Lysaker (NO)
Filed by AKER BIOMARINE HUMAN INGREDIENTS AS, Lysaker (NO)
Filed on Jul. 8, 2021, as Appl. No. 17/370,703.
Application 17/370,703 is a continuation of application No. 16/229,031, filed on Dec. 21, 2018, granted, now 11,065,267.
Claims priority of provisional application 62/608,891, filed on Dec. 21, 2017.
Claims priority of provisional application 62/725,683, filed on Aug. 31, 2018.
Prior Publication US 2021/0338697 A1, Nov. 4, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/685 (2006.01); A23D 9/00 (2006.01); A23J 7/00 (2006.01); A23L 33/115 (2016.01); A23L 33/12 (2016.01); A61K 31/202 (2006.01); C11B 1/02 (2006.01); C12P 13/00 (2006.01)

CPC A61K 31/685 (2013.01) [A23D 9/00 (2013.01); A23J 7/00 (2013.01); A23L 33/115 (2016.08); A61K 31/202 (2013.01); C11B 1/025 (2013.01); A23L 33/12 (2016.08); A23V 2002/00 (2013.01); C12P 13/001 (2013.01)]

17 Claims

1. A method for making a lysophosphatidylcholine (LPC) composition with a high content of EPA and DHA from a marine raw material containing phospholipids comprising treating the marine raw material with a phospholipase that is not native to the marine raw material to provide a phospholipase treated raw material and fractionating the phospholipase treated raw material to provide an LPC composition characterized in comprising from about 20% to about 100% LPC w/w of the composition and an omega-3 fatty acid content of from 5% to 50% w/w of the composition, a ratio of EPA:DHA of from 1:1 to 3:1 on a w/w basis or a ratio of DHA:EPA of from 1:1 to 5:1 on a w/w basis, and a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis.