US 12,076,245 B2
System and method of attaching soft tissue to an implant
Thomas J. Webster, Barrington, RI (US); and Venu Perla, Monte Vista, CO (US)
Assigned to Purdue Research Foundation, West Lafayette, IN (US)
Filed by PURDUE RESEARCH FOUNDATION, West Lafayette, IN (US)
Filed on Sep. 21, 2021, as Appl. No. 17/480,719.
Application 17/480,719 is a division of application No. 16/815,564, filed on Mar. 11, 2020, granted, now 11,141,277.
Application 13/764,259 is a division of application No. 12/544,575, filed on Aug. 20, 2009, granted, now 8,399,008, issued on Mar. 19, 2013.
Application 16/815,564 is a continuation of application No. 16/173,372, filed on Oct. 29, 2018, granted, now 10,596,001, issued on Mar. 24, 2020.
Application 16/173,372 is a continuation of application No. 15/700,931, filed on Sep. 11, 2017, abandoned.
Application 15/700,931 is a continuation of application No. 15/236,828, filed on Aug. 15, 2016, granted, now 9,788,953, issued on Oct. 17, 2017.
Application 15/236,828 is a continuation of application No. 14/528,339, filed on Oct. 30, 2014, abandoned.
Application 14/528,339 is a continuation of application No. 13/764,259, filed on Feb. 11, 2013, granted, now 8,906,402, issued on Dec. 9, 2014.
Application 12/544,575 is a continuation of application No. 11/020,587, filed on Dec. 22, 2004, granted, now 8,329,202, issued on Dec. 11, 2012.
Claims priority of provisional application 60/627,216, filed on Nov. 12, 2004.
Prior Publication US 2022/0008205 A1, Jan. 13, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/30 (2006.01); A61B 17/08 (2006.01); A61K 9/00 (2006.01); A61L 27/04 (2006.01); A61L 27/32 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 31/02 (2006.01); A61L 31/16 (2006.01); C25D 5/34 (2006.01); C25D 11/02 (2006.01)
CPC A61F 2/30771 (2013.01) [A61B 17/08 (2013.01); A61F 2/30 (2013.01); A61K 9/0024 (2013.01); A61K 9/0092 (2013.01); A61L 27/04 (2013.01); A61L 27/32 (2013.01); A61L 27/34 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 31/022 (2013.01); A61L 31/16 (2013.01); C25D 5/34 (2013.01); C25D 11/02 (2013.01); A61F 2002/30011 (2013.01); A61F 2002/30062 (2013.01); A61F 2002/30064 (2013.01); A61F 2002/3084 (2013.01); A61F 2002/3092 (2013.01); A61F 2002/30929 (2013.01); A61F 2002/3093 (2013.01); A61F 2002/30968 (2013.01); A61F 2310/00023 (2013.01); A61F 2310/0097 (2013.01); A61F 2310/00982 (2013.01); A61L 2300/414 (2013.01); A61L 2300/604 (2013.01); A61L 2300/624 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01); A61L 2430/02 (2013.01); Y10T 428/24355 (2015.01)] 12 Claims
OG exemplary drawing
 
1. A method of generating soft tissue and/or fibrocartilage tissue and/or bone on a metal implant to enhance the attachment of the metal implant to a patient's tissues, said method comprising:
implanting said implant, comprising a metal surface having nanosurface roughness produced from anodization, one or more adhered nanoparticles, or etching of the metal surface, the implant further comprising an antibiotic compound or an antimicrobial compound, wherein said implant is in contact with said patient's tissues to induce the generation of soft tissue and/or fibrocartilage tissue and/or bone on said metal implant.