US 12,076,238 B2
Heart valve prosthesis and methods of manufacture and use
Than Nguyen, Fountain Valley, CA (US); Hung Nguyen, Garden Grove, CA (US); MyKim Nguyen, Santa Ana, CA (US); Stanley Komatsu, Laguna Hills, CA (US); and Robrecht Michiels, Laguna Hills, CA (US)
Assigned to Medtronic CV Luxembourg S.A.R.L., Luxembourg (LU)
Filed by MEDTRONIC CV LUXEMBOURG S.A.R.L., Luxembourg (LU)
Filed on Jun. 19, 2022, as Appl. No. 17/844,032.
Application 17/844,032 is a continuation of application No. 17/221,895, filed on Apr. 5, 2021, abandoned.
Application 17/221,895 is a continuation of application No. 16/600,854, filed on Oct. 14, 2019, granted, now 11,284,997, issued on Mar. 29, 2022.
Application 16/600,854 is a continuation of application No. 15/295,350, filed on Oct. 17, 2016, granted, now 10,478,291, issued on Nov. 19, 2019.
Application 15/295,350 is a continuation of application No. 11/433,296, filed on May 12, 2006, granted, now 9,504,564, issued on Nov. 29, 2016.
Application 11/433,296 is a continuation in part of application No. 11/128,826, filed on May 13, 2005, granted, now 7,914,569, issued on Mar. 29, 2011.
Prior Publication US 2022/0313431 A1, Oct. 6, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/2418 (2013.01) [A61F 2/2412 (2013.01); A61F 2/2415 (2013.01); A61F 2220/005 (2013.01); A61F 2220/0058 (2013.01); A61F 2220/0075 (2013.01); A61F 2230/001 (2013.01); A61F 2230/0054 (2013.01); A61F 2230/0067 (2013.01); A61F 2230/008 (2013.01); A61F 2250/0039 (2013.01); Y10S 623/90 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A valve prosthesis comprising:
a valve body comprising a plurality of leaflets, adjoining leaflets affixed together to form commissures;
a self-expanding frame configured to radially expand from a radially contracted delivery configuration to a radially expanded deployed configuration, the self-expanding frame comprising an inflow section having a first row of cells in a circumferentially repeating pattern, the first row of cells being a proximal-most row of cells of the frame with the frame in the radially contracted delivery configuration, and an outflow section having a second row of cells in a circumferentially repeating pattern, the second row of cells being a distal-most row of cells with the frame in the radially contracted delivery configuration; and
a skirt attached to the leaflets along a joint line, a first portion of the skirt being affixed to an interior surface of the frame,
wherein an area of individual cells in the first row of cells is less than an area of individual cells in the second row of cells,
wherein when the frame is in the radially expanded deployed configuration, an outflow section diameter of the outflow section defined by a distal edge of the second row of cells is larger than an inflow section diameter of the inflow section defined by a proximal edge of the first row of cells, and
wherein the first row of cells and the second row of cells have an equal number of cells.