US 12,076,082 B2
Devices for treating calcified heart valves
Sylvain Fanier, Bordeaux (FR); Alexandre Couture, Sherbrooke (CA); Martin Brouillette, Sherbrooke (CA); Didier Tchetche, Toulouse (FR); and Raymond Regnier, Pyla sur Mer (FR)
Assigned to Med-Innov SAS, Bordeaux (FR)
Appl. No. 17/290,569
Filed by MED-INNOV SAS, Bordeaux (FR)
PCT Filed Nov. 4, 2019, PCT No. PCT/IB2019/059427
§ 371(c)(1), (2) Date Apr. 30, 2021,
PCT Pub. No. WO2020/089876, PCT Pub. Date May 7, 2020.
Claims priority of provisional application 62/754,695, filed on Nov. 2, 2018.
Prior Publication US 2021/0378744 A1, Dec. 9, 2021
Int. Cl. A61B 18/26 (2006.01); A61B 17/22 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/26 (2013.01) [A61B 2017/22025 (2013.01); A61B 2017/22062 (2013.01); A61B 2018/0022 (2013.01); A61B 2018/00369 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/266 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A balloon device for treating a calcified structure of a body tissue, the balloon device comprising:
an elongated body extending between a proximal end and a distal end and having at least one lumen extending along at least a portion thereof and defining a fluid path; and
at least one inflatable balloon secured to the elongated body and fluidly connected to the at least one lumen, the at least one lumen being fluidly connectable to a fluid source for selectively inflating and deflating the at least one inflatable balloon, the at least one inflatable balloon for treating the calcified structure when being inflated, being positioned in close proximity to the calcified structure and vibrating, wherein mechanical vibrations of the at least one inflatable balloon causing destructuration of the calcified structure, wherein the elongated body is connectable to a light source for inducing the mechanical vibrations into the at least one inflatable balloon when inflated, and wherein the at least one inflatable balloon is adapted to receive a conductive fluid therein from the fluid source; and
at least one transducer and at least one optical waveguide operatively connectable to the light source, and wherein the at least one transducer is operable to receive light from the light source and generate mechanical pulses in the conductive fluid to induce the mechanical vibrations of the at least one inflatable balloon.
 
10. A system for treating a calcified structure of a body tissue, the system comprising:
a vibrating-balloon device comprising:
an elongated body extending between a proximal end and a distal end and having at least one lumen extending along at least a portion of the elongated body and defining a fluid path therebetween; and
at least one inflatable balloon connected to the at least one lumen adjacent to the distal end of the elongated body, the at least one inflatable balloon for treating the calcified structure when being inflated, being positioned in close proximity to the calcified structure and vibrating, wherein mechanical vibrations of the at least one inflatable balloon causing destructuration of the calcified structure and wherein the elongated body is connectable to a light source for inducing mechanical vibrations into the at least one inflatable balloon when inflated;
a fluid source fluidly connectable to the at least one lumen and operable to selectively inflate and deflate the at least one inflatable balloon, wherein the at least one inflatable balloon is adapted to receive a conductive fluid therein from the fluid source; and
at least one transducer and at least one optical waveguide operatively connectable to the light source, wherein the at least one transducer is operable to receive light from the light source and generate mechanical pulses in the conductive fluid to induce the mechanical vibrations of the at least one inflatable balloon.
 
12. A method for treating a calcified structure of a body tissue, the method comprising:
providing a vibrating-balloon device comprising:
an elongated tubular body extending between a proximal end and a distal end and having at least one lumen extending along at least a portion of the elongated tubular body and defining a fluid path therebetween;
at least one inflatable balloon secured to the elongated tubular body and fluidly connected to the at least one lumen, the at least one inflatable balloon being provided with a transducer operable to receive light from a light source so as generate mechanical vibrations; and
a transducer operable to receive light from a light source so as generate the mechanical vibrations;
placing the inflatable balloon in close proximity to the body tissues;
inflating the at least one inflatable balloon using a conductive fluid source;
connecting an optical waveguide to the transducer; and
propagating pulsed light along the optical waveguide, thereby generating the mechanical vibrations within the at least one inflated balloon, thereby inducing mechanical vibrations of the calcified structure upon contact of the balloon with the body tissues to destruct the calcified structure.