US 12,405,280 B2
Portable coagulation monitoring devices, systems, and methods
Matthew Pearce, Chester (GB); Richard Hall, Chester (GB); and Joseph Anthony Dacorta, Chapel Hill, NC (US)
Assigned to Entegrion, Inc., Durham, NC (US)
Filed by Entegrion, Inc., Durham, NC (US)
Filed on Sep. 14, 2023, as Appl. No. 18/467,541.
Application 18/467,541 is a division of application No. 16/990,661, filed on Aug. 11, 2020, granted, now 11,768,210.
Application 16/990,661 is a division of application No. 14/717,117, filed on May 20, 2015, granted, now 10,739,358, issued on Jul. 22, 2022.
Application PCT/US2014/065882 is a division of application No. 12/971,013, filed on Dec. 17, 2010, granted, now 8,450,078, issued on May 28, 2013.
Application 14/717,117 is a continuation of application No. PCT/US2014/065882, filed on Nov. 17, 2014.
Application 14/717,117 is a continuation of application No. 13/897,712, filed on May 20, 2013, granted, now 9,063,161, issued on Jun. 3, 2015.
Claims priority of provisional application 61/904,489, filed on Nov. 15, 2013.
Claims priority of provisional application 61/904,523, filed on Nov. 15, 2013.
Claims priority of provisional application 61/287,780, filed on Dec. 18, 2009.
Prior Publication US 2024/0069043 A1, Feb. 29, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/86 (2006.01); G01N 11/00 (2006.01); G01N 33/49 (2006.01)
CPC G01N 33/86 (2013.01) [G01N 33/4905 (2013.01); G01N 2011/008 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of measuring coagulation response in a blood sample, the method comprising:
receiving a sample of blood between and in contact with a first surface of a first member and a second surface of a second member;
linearly moving and oscillating the first member to cause the first surface to oscillate relative to the second surface of the second member at a predetermined speed causing the sample of blood to coagulate and bind to the first and second surfaces and inducing movement of the second member from a stationary position responsive to the movement of the first member via the coagulated sample of blood; and
measuring mechanical displacement between the first and second members as indicative of a coagulation response of the sample of blood.