US 12,405,279 B2
Method for preparing a sample
Aline Pehla, Hennigsdorf (DE); Stefan Kirsch, Hennigsdorf (DE); and Darius Wilson, Lorrach (DE)
Assigned to B.R.A.H.M.S GMBH, Hennigsdorf (DE)
Filed by B.R.A.H.M.S GmbH, Hennigsdorf (DE)
Filed on Mar. 31, 2022, as Appl. No. 17/710,329.
Application 17/710,329 is a continuation of application No. 16/646,798, granted, now 11,327,082, previously published as PCT/EP2018/074725, filed on Sep. 13, 2018.
Claims priority of application No. 17190912 (EP), filed on Sep. 13, 2017; and application No. 18161091 (EP), filed on Mar. 9, 2018.
Prior Publication US 2022/0221474 A1, Jul. 14, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/74 (2006.01); G01N 33/86 (2006.01)
CPC G01N 33/74 (2013.01) [G01N 33/86 (2013.01); G01N 2800/222 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01)] 17 Claims
 
1. A method comprising:
preparing a sample comprising bodily fluid from a patient, and an antibody which binds to proADM or fragment(s) thereof,
wherein the patient has platelet levels below 150,000 platelets per microliter of
blood and/or thrombocytopenia and/or disseminated intravascular coagulation (DIC), and
wherein the level of detectable proADM or fragment(s) in the sample is equal to or greater than 6.5 nmol/l±20%.