US 12,404,305 B2
Chimeric polypeptides and uses thereof
Stuart A. Sievers, Van Nuys, CA (US); and Jed J. W. Wiltzius, Winchester, MA (US)
Assigned to Kite Pharma, Inc., Santa Monica, CA (US)
Filed by Kite Pharma, Inc., Santa Monica, CA (US)
Filed on Dec. 20, 2022, as Appl. No. 18/069,151.
Application 18/069,151 is a continuation of application No. 15/929,737, filed on May 19, 2020, granted, now 11,572,388.
Application 15/929,737 is a continuation of application No. 16/138,331, filed on Sep. 21, 2018, abandoned.
Claims priority of provisional application 62/562,223, filed on Sep. 22, 2017.
Prior Publication US 2023/0287054 A1, Sep. 14, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/00 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61K 47/65 (2017.01); A61P 35/02 (2006.01); C07K 4/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 16/28 (2006.01); C07K 16/44 (2006.01); C12N 15/62 (2006.01); C12N 15/85 (2006.01)
CPC C07K 14/003 (2013.01) [A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); A61K 47/65 (2017.08); A61P 35/02 (2018.01); C07K 4/00 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 16/2803 (2013.01); C07K 16/44 (2013.01); C12N 15/62 (2013.01); C12N 15/85 (2013.01); C07K 2317/32 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2319/40 (2013.01)] 4 Claims
 
1. A fusion protein comprising:
a first polypeptide and a second polypeptide covalently linked by a peptide comprising the amino acid sequence selected from the group consisting of:
(i) GGGSGKPGSGEGGGS (SEQ ID NO: 7);
(ii) GGGSGKPGSGEGGGGS (SEQ ID NO: 8);
(iii) GGGGSGKPGSGGGGS (SEQ ID NO: 9);
(iv) GGGGSGKPGSGEGGS (SEQ ID NO: 10)
(v) GGGGSGKPGSGEGGGS (SEQ ID NO: 11); and
(vi) GGGGSGKPGSGEGGGGS (SEQ ID NO: 12).