US 12,404,304 B1
Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same
William H. Andrews, Reno, NV (US); Christopher A. Foster, Carmichael, CA (US); Lancer K. Brown, Sparks, NV (US); Laura A. Briggs, Reno, NV (US); October Pawlik, Sparks, NV (US); Penelope Burke, Reno, NV (US); Federico C. A. Gaeta, Mountain View, CA (US); Beril Karakas, Reno, NV (US); Jessica Wheeler, Sparks, NV (US); Mieczyslaw A. Piatyszek, Morgan Hill, CA (US); Munirathnam Chaguturu, Lawrence, KS (US); Jian Zhang, Fremont, CA (US); Tom Kerley, Gardnerville, NV (US); and Hamid Mohammadpour, Reno, NV (US)
Assigned to Sierra Sciences, LLC, Reno, NV (US)
Filed by Sierra Sciences, LLC, Reno, NV (US)
Filed on May 20, 2020, as Appl. No. 16/879,075.
Application 16/879,075 is a continuation of application No. 14/163,983, filed on Jan. 24, 2014, abandoned.
Application 14/163,983 is a continuation of application No. 12/727,086, filed on Mar. 18, 2010, abandoned.
Application 12/727,086 is a continuation in part of application No. 12/578,512, filed on Oct. 13, 2009, abandoned.
Application 12/727,086 is a continuation in part of application No. 12/270,552, filed on Nov. 13, 2008, abandoned.
Claims priority of provisional application 61/182,931, filed on Jun. 1, 2009.
Claims priority of provisional application 61/104,997, filed on Oct. 13, 2008.
Claims priority of provisional application 60/988,043, filed on Nov. 14, 2007.
Int. Cl. C07D 413/14 (2006.01); C07D 215/06 (2006.01); C07D 231/22 (2006.01); C07D 279/02 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 405/06 (2006.01); C07D 409/06 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 493/08 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07H 17/04 (2006.01); C07K 9/00 (2006.01); C12N 15/01 (2006.01)
CPC C07K 9/003 (2013.01) [C07D 215/06 (2013.01); C07D 231/22 (2013.01); C07D 279/02 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 493/08 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07H 17/04 (2013.01); C12N 15/01 (2013.01)] 4 Claims
 
1. A method for enhancing telomerase reverse transcriptase (TERT) expression in an individual, the method comprising:
administering to the individual an azole compound described by one of the following structures:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry
determining the amount of expression of TERT in a cell of the individual after administration with the compound.