CPC C07D 271/06 (2013.01) | 20 Claims |
1. A process for preparation of a compound of formula (1) or a salt thereof,
![]() comprising:
i) reacting a compound of formula (7) in a presence of a compound of formula (R)3SiOM, where R is selected from C1-C5 alkyl or aryl and M is selected from Na or K or Li, in a solvent at a temperature between 50° C. and reflux temperature of the solvent to provide the compound of formula (1) in a reaction mixture;
![]() ii) adding an acid or silicagel to said reaction mixture;
iii) isolating a solid form of the compound of formula (1) from alkyl acetate or an alcohol or a mixture thereof; and
iv) optionally salifying the compound of formula (1).
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