US 12,403,477 B2
Method and device for creating organotypic lumen models in a microwell plate
David J. Beebe, Monona, WI (US); and Patrick H. McMinn, Madison, WI (US)
Assigned to Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed by Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed on Jun. 12, 2024, as Appl. No. 18/741,450.
Application 18/741,450 is a division of application No. 17/004,268, filed on Aug. 27, 2020, granted, now 12,151,244.
Prior Publication US 2024/0367174 A1, Nov. 7, 2024
Int. Cl. B01L 3/00 (2006.01); B29C 39/02 (2006.01); B29L 31/40 (2006.01)
CPC B01L 3/5085 (2013.01) [B29C 39/02 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0893 (2013.01); B01L 2300/12 (2013.01); B29K 2995/0008 (2013.01); B29L 2031/40 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A device for creating a lumen in a microenvironment, comprising:
a microwell plate defining a plurality of wells arranged in rows and columns, each of the plurality of wells defined by at least one sidewall having first and second openings therein;
a plurality of rods, each rod selectively moveable between a first position wherein each rod is removed from corresponding first and second openings in each of the at least one sidewall defining the plurality of wells and a second position wherein each rod is inserted through the corresponding first and second openings in each of the at least one sidewall defining the plurality of wells; and
a fixture interconnected to the plurality of rods, the fixture configured for moving the plurality of rods between the first and second positions.