	US 12,403,453 B2
	Stationary phase medium for adsorption chromatography and manufacturing method thereof
Tsung-Han Tu, Taoyuan (TW); Chia-Wei Lin, Taoyuan (TW); Shih-Yu Wang, Taoyuan (TW); Hui Chen, Taoyuan (TW); Min-Shyan Sheu, Taoyuan (TW); and Shih-Horng Yang, Taoyuan (TW)
Assigned to Tantti Laboratory Inc., Taoyuan (TW)
Filed by Tantti Laboratory Inc., Taoyuan (TW)
Filed on Apr. 26, 2022, as Appl. No. 17/729,153.
Claims priority of application No. 111114908 (TW), filed on Apr. 20, 2022.
Prior Publication US 2023/0338924 A1, Oct. 26, 2023
Int. Cl. B01J 20/26 (2006.01); B01D 15/20 (2006.01); B01J 20/28 (2006.01); B01J 20/285 (2006.01); B01J 20/288 (2006.01); B01J 20/30 (2006.01)

CPC B01J 20/285 (2013.01) [B01D 15/206 (2013.01); B01J 20/267 (2013.01); B01J 20/28004 (2013.01); B01J 20/28016 (2013.01); B01J 20/28052 (2013.01); B01J 20/28085 (2013.01); B01J 20/28095 (2013.01); B01J 20/288 (2013.01); B01J 20/3021 (2013.01); B01J 20/3085 (2013.01); B01J 2220/54 (2013.01)]

15 Claims

1. A stationary phase medium for adsorption chromatography comprising:

a plurality of porous particles made of cross-linked polymeric material with a Feret diameter ranging from 25 μm to 500 μm and having a porosity ranging from 70% to 90%, each being formed with multiple spherical macropores having a diameter ranging from 3 μm to 10 μm, wherein the spherical macropores are interconnected with one another via connecting pores to constitute a porous network with an average diameter ranging from 0.2 μm to 6 μm; and

wherein the porous particles are in form of irregular granules having a Feret aspect ratio distribution between 1.0 and 3.5 with a standard deviation ranging from 1.2 to 2.2.