US 12,403,329 B2
Updating proton stopping power maps for proton radiation therapy treatment planning
Don Frederic Dejongh, Batavia, IL (US); and Ethan Alan Dejongh, Aurora, IL (US)
Assigned to ProtonVDA LLC, Naperville, IL (US)
Filed by ProtonVDA LLC, Naperville, IL (US)
Filed on Oct. 12, 2023, as Appl. No. 18/485,563.
Claims priority of provisional application 63/415,525, filed on Oct. 12, 2022.
Prior Publication US 2024/0131360 A1, Apr. 25, 2024
Int. Cl. A61N 5/10 (2006.01); A61B 6/42 (2024.01)
CPC A61N 5/1039 (2013.01) [A61N 5/103 (2013.01); A61B 6/4258 (2013.01); A61N 2005/1087 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method comprising:
performing image registration to account for differences between an original image and an updated image;
updating an original relative stopping power (RSP) map corresponding to the original image using individual proton measurement data, wherein the individual proton measurement data are associated with the updated image;
comparing the updated RSP map to the original RSP map, wherein the original image corresponds to the original RSP map; and
quantifying changes between the updated map and the original RSP map.
 
19. A system comprising:
a source for generating a pencil beam of protons;
a scanning element for steering the pencil beam of protons;
a plurality of tracking detectors for generating photons, the photons corresponding to the pencil beam of protons interacting with an object;
a residual range detector; and
a computing system for receiving signals from the plurality of tracking detectors and the residual range detector, the computing system configured to:
perform image registration to account for differences between an original image and an updated image;
update an original RSP map corresponding to the original image using individual proton measurement data, wherein the individual proton measurement data are associated with the updated image;
compare the updated RSP map to the original RSP map, wherein the original image corresponds to the original RSP map; and
quantify changes between the updated map and the original RSP map.