| CPC A61N 5/1031 (2013.01) [G16H 20/40 (2018.01)] | 20 Claims |

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1. A computer system, comprising:
a processor; and
memory coupled to the processor and comprising instructions that, when executed, cause the processor to perform a method used for planning radiation treatment comprising spot scanning of a target volume, the method comprising:
accessing, from the memory, a first arrangement of a plurality of spots inside the target volume;
accessing, from the memory, a respective dose distribution for each spot of the plurality of spots inside the target volume;
determining for said each spot whether differences between the respective dose distribution for a spot and respective dose distributions for spots that are neighbors to the spot satisfy a criterion;
identifying a first set of spots that do not satisfy the criterion; and
increasing a number of spots inside regions of the target volume that include locations of the first set of spots to produce a second arrangement of a plurality of spots inside the target volume.
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