US 12,403,228 B2
Monitoring device for recirculation analysis
Silvie Krause, Melsungen (DE); Henrik Wolff, Melsungen-Adelshausen (DE); and Marten Jakob, Klein Lengden (DE)
Assigned to B. Braun Avitum AG, Melsungen (DE)
Appl. No. 17/433,365
Filed by B. Braun Avitum AG, Melsungen (DE)
PCT Filed Feb. 25, 2020, PCT No. PCT/EP2020/054833
§ 371(c)(1), (2) Date Aug. 24, 2021,
PCT Pub. No. WO2020/173900, PCT Pub. Date Sep. 3, 2020.
Claims priority of application No. 10 2019 104 738.2 (DE), filed on Feb. 25, 2019.
Prior Publication US 2022/0168482 A1, Jun. 2, 2022
Int. Cl. A61M 1/16 (2006.01); G16H 20/40 (2018.01)
CPC A61M 1/1619 (2014.02) [G16H 20/40 (2018.01)] 11 Claims
OG exemplary drawing
 
1. An extracorporeal blood treatment machine comprising:
a filter having a blood inlet line configured to receive blood from a patient, a blood outlet line configured to return the blood to the patient, a dialysis liquid inlet line configured to receive fresh dialysis liquid, a dialysis liquid outlet line configured to discharge used dialysis liquid, and a semipermeable membrane configured to filter pollutants from the blood into the fresh dialysis liquid to convert the fresh dialysis liquid into the used dialysis liquid;
a measuring cell in the dialysis liquid outlet line; and
a monitoring device operatively connected to the measuring cell, wherein the monitoring device is configured to:
detect a signal from the measuring cell continuously representing a concentration of pollutants in the used dialysis liquid and to automatically evaluate a signal course with respect to at least one predetermined signal course indicator or signal course pattern for an existing blood recirculation;
differentiate the signal for evaluation in order to calculate a differential signal and compare it with a threshold value, wherein a certain frequency or duration of threshold value overruns and/or a one-time threshold value overrun of said threshold value or of another threshold value is recognized as the at least one predetermined signal course indicator or signal course pattern for the existing blood recirculation; and
automatically initiate a recirculation measurement or automatically output a request for initiating a recirculation measurement to a user upon determination of the at least one predetermined signal course indicator or signal course pattern.