US 12,403,220 B2
Scaffolds for cartilage regeneration and method for treatment of cartilage defects using the same
Jangho Kim, Gwangju (KR); Jong Keun Seon, Gwangju (KR); and Sunho Park, Gwangju (KR)
Assigned to INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, Gwangju (KR)
Filed by INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, Gwangju (KR)
Filed on Sep. 20, 2021, as Appl. No. 17/479,057.
Prior Publication US 2023/0211049 A1, Jul. 6, 2023
Int. Cl. A61L 27/38 (2006.01); A61L 27/36 (2006.01)
CPC A61L 27/3834 (2013.01) [A61L 27/365 (2013.01); A61L 27/3654 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01); A61L 2430/02 (2013.01); A61L 2430/06 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A scaffold comprising:
a film having a plurality of linear nano-patterns formed and aligned in one direction on a surface of the film, the film having the plurality of nano-patterns prepared by a process comprising preparing a film having a surface on which the plurality of linear nano-patterns do not exist and forming the plurality of linear nano-patterns on the surface of the film; and
stem cells adhered to the plurality of linear nano-patterns,
wherein the plurality of linear nano-patterns include a ridge and a groove having each independently a width of 100 to 1,000 nm,
wherein the plurality of linear nano-patterns have a height of 100 to 1000 nm.