US 12,403,217 B2
Biodegradeable implant comprising coated metal alloy product
Alexander Kopp, Aachen (DE)
Assigned to KARL LEIBINGER ASSET MANAGEMENT GMBH & CO. KG, Muhlheim (DE)
Appl. No. 17/296,244
Filed by Karl Leibinger Asset Management Gmbh & Co. KG, Mühlheim (DE)
PCT Filed Nov. 22, 2019, PCT No. PCT/EP2019/082226
§ 371(c)(1), (2) Date May 23, 2021,
PCT Pub. No. WO2020/104653, PCT Pub. Date May 28, 2020.
Claims priority of application No. 102018129604.5 (DE), filed on Nov. 23, 2018.
Prior Publication US 2022/0016315 A1, Jan. 20, 2022
Int. Cl. A61L 27/32 (2006.01); A61L 27/30 (2006.01); A61L 27/58 (2006.01); C22C 18/00 (2006.01); C22C 23/00 (2006.01); C25D 11/02 (2006.01); C25D 11/30 (2006.01); C25D 11/36 (2006.01)
CPC A61L 27/32 (2013.01) [A61L 27/306 (2013.01); A61L 27/58 (2013.01); C22C 18/00 (2013.01); C22C 23/00 (2013.01); C25D 11/024 (2013.01); C25D 11/026 (2013.01); C25D 11/30 (2013.01); C25D 11/36 (2013.01); A61L 2420/02 (2013.01); A61L 2430/02 (2013.01)] 18 Claims
 
1. A biodegradable implant comprising a magnesium or zinc alloy product coated on its surface with a coating layer comprising at least three substances being
a. a metal oxide of a metal selected from rare-earth elements, Mg, Ca, Zn, Zr, Cu, Sr, Li, Mn or Ag; and/or
b. a metal phosphate of a metal selected from rare-earth elements, Mg, Ca, Zn, Zr, Cu, Sr, Li, Mn or Ag;
wherein the magnesium alloy is selected form the group consisting of a magnesium silver alloy (Mg—Ag), a Mg—Y-RE alloy containing yttrium and at least one additional rare earth element (RE), and a magnesium alloy comprising calcium and zinc, or
wherein the zinc alloy is a selected from the group consisting of a zinc-magnesium alloy with the addition of calcium (Zn—Ca—Mg or Zn—Mg—Ca), a zinc-silver alloy (Zn—Ag) with or without the addition of magnesium (Zn—Ag—Mg or Zn—Mg—Ag), a zinc-strontium alloy with the addition of magnesium (Zn—Sr—Mg or Zn—Mg—Sr), a zinc-lithium alloy with or without the addition of magnesium (Zn—Li—Mg) or (Zi—Mg—Li), a zinc-calcium alloy with the addition of magnesium (Zn—Ca—Mg or Zn—Mg—Ca), and a zinc-manganese alloy (Zn—Mn) with or without the addition of magnesium (Zn—Mn—Mg or Zn—Mg—Mn).