US 12,403,171 B2
Plant extract highly concentrated in safranal, production method and uses thereof
David Gaudout, Carignan de Bordeaux (FR); Stephane Rey, Montelimar (FR); Benoit Lemaire, Libourne (FR); Benjamin Moras, Montelimar (FR); and Marion Dumoulin, Bordeaux (FR)
Assigned to ACTIV'INSIDE, Beychac et Caillau (FR)
Filed by ACTIV'INSIDE, Beychac et Caillau (FR)
Filed on Jan. 24, 2023, as Appl. No. 18/100,700.
Application 18/100,700 is a continuation of application No. 16/320,847, granted, now 11,590,193, previously published as PCT/EP2017/069200, filed on Jul. 28, 2017.
Prior Publication US 2023/0165927 A1, Jun. 1, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61Q 19/00 (2006.01); A61K 8/9789 (2017.01); A61K 8/9794 (2017.01); A61K 31/11 (2006.01); A61K 36/88 (2006.01); A61P 15/10 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01)
CPC A61K 36/88 (2013.01) [A61K 8/9789 (2017.08); A61K 8/9794 (2017.08); A61K 31/11 (2013.01); A61P 15/10 (2018.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61Q 19/00 (2013.01); A61K 2236/15 (2013.01); A61K 2236/33 (2013.01); A61K 2236/331 (2013.01); A61K 2236/333 (2013.01); A61K 2236/35 (2013.01)] 12 Claims
 
1. A thermally treated, encapsulated plant extract in powder form containing at least 0.2% of safranal by weight as measured by HPLC, the thermally treated encapsulated plant extract obtained by the method comprising:
a) extracting a plant-based raw material containing safranal, wherein the plant-based raw material is selected from the group consisting of Crocus sativus, Centaurea sibthorpii, Centaurea consanguinea, Centaurea amanicola, Erodium cicutarium, Chinese green tea, Calycopteris floribunda, Crocus heuffelianus, Sambucus nigra, Gardenia jasminoides, Citrus limon, Cuminum cyminum L., and Achillea distans with an extraction solution to provide a liquid extract;
b) impregnating the liquid extract onto a bulking agent selected from the group consisting of maltodextrin, sugars, silica, and acacia gum to form an encapsulated plant extract; and
c) subjecting the encapsulated plant extract to thermal treatment.
 
9. A cosmetic, food, nutritional or medicinal composition comprising between 0.1 and 100% by weight of the thermally treated, encapsulated plant extract of claim 1.
 
12. A method for ameliorating one or more symptoms of depression, anxiety, erectile dysfunction or premenstrual disorder in a subject, the method comprising administering to the subject the cosmetic, food, nutritional or medicinal composition of claim 9.