US 12,403,128 B2
Compositions and methods for blocking sodium channels
Manoj K. Patel, Charlottesville, VA (US); and Mirko Rivara, San Polo di Torrile (IT)
Assigned to Univerity of Virginia Patent Foundation, Charlottesville, VA (US); and Mirko Rivara, Charlottesville, VA (US)
Filed by University of Virginia Patent Foundation, Charlottesville, VA (US); and Mirko Rivara, San Polo Torrile (IT)
Filed on Jun. 25, 2021, as Appl. No. 17/304,828.
Application 17/304,828 is a continuation of application No. 16/480,300, granted, now 11,090,289, previously published as PCT/US2018/015059, filed on Jan. 24, 2018.
Claims priority of provisional application 62/449,812, filed on Jan. 24, 2017.
Prior Publication US 2022/0047554 A1, Feb. 17, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/4164 (2006.01); A61K 31/4184 (2006.01); A61P 25/08 (2006.01)
CPC A61K 31/4164 (2013.01) [A61K 31/4184 (2013.01); A61P 25/08 (2018.01)] 2 Claims
 
1. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound having the structure:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, prodrug, tautomer, stereoisomer, hydrate, or solvate thereof.