US 12,403,116 B2
Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof
Xiaobo Sun, Beijing (CN); Yu Tian, Beijing (CN); and Xiao Sun, Beijing (CN)
Assigned to CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUE OF MEDICINAL PLANT DEVELOPMENT, Beijing (CN)
Appl. No. 18/271,036
Filed by CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF MEDICINAL PLANT DEVELOPMENT, Beijing (CN)
PCT Filed Aug. 15, 2022, PCT No. PCT/CN2022/112512
§ 371(c)(1), (2) Date Sep. 3, 2024,
PCT Pub. No. WO2023/165094, PCT Pub. Date Sep. 7, 2023.
Claims priority of application No. 202210205661.2 (CN), filed on Mar. 4, 2022.
Prior Publication US 2025/0177342 A1, Jun. 5, 2025
Int. Cl. A61K 31/24 (2006.01); A61K 31/235 (2006.01); A61P 9/10 (2006.01); C07C 68/00 (2020.01); C07C 69/76 (2006.01); C07C 205/59 (2006.01)
CPC A61K 31/24 (2013.01) [A61K 31/235 (2013.01); A61P 9/10 (2018.01); C07C 68/00 (2013.01); C07C 69/76 (2013.01); C07C 205/59 (2013.01)] 20 Claims
 
1. A compound represented by the following formula:

OG Complex Work Unit Chemistry
wherein R is

OG Complex Work Unit Chemistry
and
X is H, nitro, amino, F, Cl, Br, or I.