US 12,403,102 B2
Pharmaceutical compositions containing paracetamol derivatives and use thereof
Vinayshankar Tripathi, Indore (IN); and Akshay Nikhil Patel, Indore (IN)
Assigned to M/S Status Projects Private Limited, Indore (IN)
Filed by M/S Status Projects Private Limited, Indore (IN)
Filed on Sep. 28, 2022, as Appl. No. 17/954,557.
Prior Publication US 2024/0115522 A1, Apr. 11, 2024
Int. Cl. A61K 31/136 (2006.01); A61K 9/00 (2006.01)
CPC A61K 31/136 (2013.01) [A61K 9/0056 (2013.01)] 20 Claims
 
1. A pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I):

OG Complex Work Unit Chemistry
wherein
R1 is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C2-C7 acyl, or C1-C6 aralkyl;
R2 is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl;
R3 is C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, or C1-C6 aralkyl,
Y is oxygen or sulfur; and
X is halogen, or a pharmaceutically acceptable salt or prodrug thereof; a pharmaceutically effective carrier; and wherein said therapeutically effective amount is between non-zero and less than 500 mg.