| CPC A61F 2/2418 (2013.01) [A61F 2/2409 (2013.01); A61F 2/2436 (2013.01); A61F 2002/9534 (2013.01); A61F 2220/0008 (2013.01); A61F 2230/005 (2013.01); A61F 2230/0065 (2013.01); A61F 2230/0078 (2013.01)] | 20 Claims |

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1. A method of implanting a prosthetic heart valve at a native tricuspid valve region having a native valve annulus and a plurality of native leaflets, comprising:
delivering a prosthetic heart valve to the native tricuspid valve region via the inferior vena cava or the superior vena cava, the prosthetic heart valve contained within an interior of a sheath of a delivery apparatus, the prosthetic heart valve comprising:
a radially compressible and expandable frame assembly comprising an inflow end, an outflow end, and a double-body structure having an annular inner frame and an annular outer frame, the inner frame having a main body comprising a plurality of circumferentially extending rows of angled struts and the annular outer frame having a main body and an atrial flange portion configured to contact an atrial face of the native valve annulus;
a plurality of prosthetic leaflets mounted within the inner frame for regulating the flow of blood in one direction through the inner frame; and
a plurality of ventricular anchors, each comprising a free end portion and a fixed end portion connected to and extending from the frame assembly at a location spaced from the outflow end of the frame assembly; and
deploying the prosthetic heart valve from the sheath such that the main bodies of the inner and outer frames expand within the native annulus, the atrial flange portion is deployed in an atrium adjacent the native annulus, and each of the plurality of ventricular anchors extend behind one of the native leaflets.
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