US 12,402,855 B2
System and method for continuous non-invasive ultrasonic monitoring of blood vessels and central organs
Sheng Xu, La Jolla, CA (US); Chonghe Wang, La Jolla, CA (US); Zhuorui Zhang, La Jolla, CA (US); Baiyan Qi, La Jolla, CA (US); and Muyang Lin, La Jolla, CA (US)
Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
Appl. No. 17/604,616
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
PCT Filed Apr. 20, 2020, PCT No. PCT/US2020/028983
§ 371(c)(1), (2) Date Oct. 18, 2021,
PCT Pub. No. WO2020/215075, PCT Pub. Date Oct. 22, 2020.
Claims priority of provisional application 62/972,358, filed on Feb. 10, 2020.
Claims priority of provisional application 62/835,857, filed on Apr. 18, 2019.
Prior Publication US 2022/0175340 A1, Jun. 9, 2022
Int. Cl. A61B 8/06 (2006.01); A61B 8/00 (2006.01); A61B 8/08 (2006.01); B06B 1/06 (2006.01)
CPC A61B 8/06 (2013.01) [A61B 8/4236 (2013.01); A61B 8/4263 (2013.01); A61B 8/4444 (2013.01); A61B 8/4488 (2013.01); A61B 8/461 (2013.01); A61B 8/488 (2013.01); A61B 8/54 (2013.01); B06B 1/0629 (2013.01); B06B 1/0681 (2013.01); B06B 2201/76 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method for monitoring a patient using an ultrasonic probe, comprising:
attaching a conformable two-dimensional piezoelectric transducer array having a plurality of phased array piezoelectric transducer elements on an epidermal surface of a patient so that the conformable two-dimensional piezoelectric transducer array conforms to a shape of the epidermal surface wherein the phased array piezoelectric transducer elements have a pitch about equal to one ultrasound wavelength at which the plurality of phased array piezoelectric transducer elements operate operating the plurality of phased array piezoelectric transducer elements as a phased array to transmit a focused ultrasonic beam so that the focused ultrasonic beam penetrates to a depth of at least 4 cm for continuous hemodynamic monitoring of central organs and at least 6 cm for cardiac activity monitoring;
receiving ultrasound waves from the patient using the plurality of phased array piezoelectric transducer elements; and
displaying an indication of the received ultrasound waves.