US 12,402,827 B2
Methods of ventricular arrhythmia localization using a 3D heart model
Barry Yomtov, Marblehead, MA (US); and Tracy K. Ginnings, Salem, VA (US)
Assigned to KardioNav, Inc., Fort Mills (SC)
Filed by KardioNav, Inc., Mt. Olive, NJ (US)
Filed on Jul. 11, 2021, as Appl. No. 17/372,470.
Claims priority of provisional application 63/050,542, filed on Jul. 10, 2020.
Prior Publication US 2022/0007990 A1, Jan. 13, 2022
Int. Cl. A61B 5/367 (2021.01); A61B 5/055 (2006.01); A61B 5/28 (2021.01); A61B 5/339 (2021.01)
CPC A61B 5/367 (2021.01) [A61B 5/055 (2013.01); A61B 5/28 (2021.01); A61B 5/339 (2021.01)] 7 Claims
OG exemplary drawing
 
1. A method of generating a modified 3D heart model with arrhythmia localization, comprising:
generating image data of a heart of a patient using a magnetic resonance imaging (MRI) device or a computed tomography (CT) imaging device;
generating by a processing unit coupled to a memory a three-dimensional (3D) heart model of the heart using the image data, the 3D heart model comprising myocardium wall thickness measurements of the heart derived from the image data;
capturing using a 3D camera a 3D image of the patient's torso including the location of ECG electrodes on the patient used to collect electrocardiogram (ECG) data;
merging by the processing unit the 3D image of the patient's torso with the 3D heart model to form a torso and heart model comprising positions of the ECG electrodes relative to the heart model based on the location of the ECG electrodes in the 3D image;
generating by the processing unit an activation map of the heart by combining ECG data, recorded using the ECG electrodes during ventricular tachycardia (VT) of the heart, with the heart and torso model providing the positions of the ECG electrodes;
performing by the processing unit an inverse solution calculation, using the ECG data recorded during VT and the positions of the ECG electrodes in the heart and torso model, to identify a VT exit point on the activation map;
modifying by the processing unit the 3D heart model to include the VT exit point identified on the activation map; and
delivering, based on the VT exit point identified in the modified 3D heart model, ablation therapy to the identified VT exit point location to treat the ventricular tachycardia.