CPC G01N 33/49 (2013.01) [B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); G01N 1/4077 (2013.01); G01N 33/491 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/06 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0439 (2013.01); G01N 33/5002 (2013.01)] | 16 Claims |
1. A system comprising:
a channel to receive whole blood comprised of blood cells and plasma, the whole blood forming a fluid column in the channel;
a plurality of acoustic transducers including a first acoustic transducer to apply acoustic force to the fluid column in the channel to form a fluid layer in the channel, the fluid layer comprising the plasma, the fluid layer being substantially free of the blood cells, and the fluid layer being adjacent to a particle layer comprising the blood cells;
an optical detector that is aligned with the fluid layer to perform detection on the fluid layer to detect an analyte through measurement of the fluid layer;
wherein the first acoustic transducer is configured to apply the acoustic force at a first region of the channel;
wherein the plurality of acoustic transducers includes a second acoustic transducer configured to apply acoustic force at a different region of the channel than the first region; and
wherein the optical detector comprises a spectrometer.
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