CPC C07D 455/02 (2013.01) [A61P 25/26 (2018.01); C07D 217/24 (2013.01); C07D 237/32 (2013.01); C07D 239/90 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 403/10 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07B 2200/05 (2013.01)] | 14 Claims |
1. A compound represented by the formula:
wherein
R1 is an optionally substituted C1-6 alkylsulfonyl group, an optionally substituted mono- or di-C1-6 alkylaminosulfonyl group, an optionally substituted 3- to 6-membered cyclylsulfonyl group, a formylcarbonyl group, a carboxycarbonyl group, a carbamoylcarbonyl group, an optionally substituted C1-6 alkyl-carbonyl group, an optionally substituted C1-6 alkoxy-carbonyl group, an optionally substituted mono- or di-C1-6 alkyl-carbamoyl group, an optionally substituted C1-6 alkyl-carbonyl-carbonyl group, an optionally substituted C1-6 alkoxy-carbonyl-carbonyl group, an optionally substituted mono- or di-C1-6 alkyl-carbamoyl-carbonyl group or an optionally substituted 3- to 6-membered cyclylcarbonyl group;
R2 and R3 are each independently a hydrogen atom, an optionally substituted C1-6 alkyl group or a halogen atom;
X is an optionally substituted methylene group, NRa or an oxygen atom;
Ra is a hydrogen atom or an optionally substituted C1-6 alkyl group;
Y and Z are each independently a carbon atom, CH or a nitrogen atom;
is Z—Y or Z═Y;
Ring A is an optionally further substituted 5- or 6-membered nitrogen-containing non-aromatic heterocycle;
L is an optionally substituted methylene group, an oxygen atom, —O-L1-, -L1-O— or -L1-L2;
L1 and L2 are each independently an optionally substituted methylene group; and
Ring B is an optionally further substituted 4- to 7-membered ring,
or a salt thereof.
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